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Therapeutic Index


Each Uncoated Tablet Contains:-

Adefovir Dipivoxil……..10mg
Approved colours used

Indications :
Adevera® (adefovir dipivoxil) is a prescription medicine used to treat chronic infection with H - B virus (HBV) adeverain adults. Adevera does not cure chronic Hepatitis B, and it does not reduce the risk of spreading Hepatitis B to others. An antiviral medicine, Adevera helps stop H - B virus (HBV) from multiplying by blocking HBV DNA polymerase, an enzyme that is necessary for the replication of the virus in the body.

Adefovir works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B vvirus (HBV) to reproduce in the body. It is approved for the treatment of chronic hepatitis B in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferase (primarily ALT) or histologically active disease. Adefovir is a failed treatment for HIV due to the severity and frequency of kidney toxicity when dosed at 60 or 120 mg. However, trials have found the 10 mg dose of adefovir to be an effective and safe treatment for HBV.The main benefit of adefovir over lamivudine (the first NRTI approved for the treatment of hepatitis B) is that it takes a much longer period of time before the virus develops resistance to it.

Adevera® (adefovir dipivoxil) is provided as a 10 mg tablet that you take once a day by mouth. Adevera can be taken with or without food. If you have or develop kidney problems, your doctor may tell you to take the pill on a different schedule.

Doses of adefovir dipivoxil 500 mg daily for 2 weeks and 250 mg daily for 12 weeks have been associated with gastrointestinal side effects effects. If overdose occurs the patient occurs the patients must be monitored for evidence of toxicity, and  standard supportive  treatment applied as necessary.
Following a 10 mg single dose of of HEPSERA, a four-hour hemidialysis session removed approximately 35% of the adefovir dose.

HEPSERA is contraindicated in patients with previously demonstrated hypersensitivity to any of the components of the product.

Presentations :  30 tablets
                         MRP                Retailer               Stockist
575.00              460.00                  414.00

PVC Bottle with carton
Adevera     Blister pack of 10 capsules





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