Therapeutic Index

FETRASIL can only be prescribed by a medical doctor.If FETRASIL is right for you, your doctor will determine the starting dose. FETRASIL comes in three different
strength capsules (5 mg, 10 mg, and 15 mg). The recommended initial starting dose of FETRASIL is one 10 mg capsule per day.
© 2007 Taj Pharmaceuticals Ltd., India. All rights reserved.

FETRASIL works by acting on the appetite control center in the brain. Studies have shown that using FETRASIL, along with a reduced-calorie diet and exercise, helped patients lose weight and maintain weight loss for up to two years.1,2

The active ingredient in FETRASIL, sibutramine, works in the area of the brain that signals the sense of fullness (satiety).1 FETRASIL does not suppress appetite, which is your signal to start eating.

FETRASIL blocks the re-uptake of the brain chemicals (serotonin and norepinephrine) which help regulate the sense of fullness.1 Fullness is your signal to stop eating. Having a sense of fullness, or satiety, means you may feel satisfied with less food.

Sibutramine should be used in conjunction with a reduced calorie diet. Always consult your physician before beginning any diet or exercise program.3
Clinical Experience

Sibutramine, the active ingredient in FETRASIL, has been extensively studied throughout the world. It has been studied in more than 100 clinical trials involving more than 12,000 patients. Approximately 14 million patients in more than 75 countries have used sibutramine for the treatment of obesity since it was approved in 1997.

In studies, sibutramine in combination with diet and exercise was effective in producing and maintaining significant weight loss in the majority of obese patients compared to diet and exercise alone.

1. Heal DJ, Aspley S, Prow MR et al. Sibutramine, a novel anti-obesity drug. A review of the pharmacological evidence to dfferentiate it from d-ampetamine and d-fenfluramine. Int J Obes. 1998;22(supp 1):S18-S28.

2. James WPT, Astrup A, Finer N, et al. Effect of sibutramine on weight mainteancne after weight loss; a randomized trial. Lancet.2000;356;2119-2125.

3. FETRASIL Prescribing Information, Taj Pharmaceuticals Ltd..

4. Data on file, Taj Pharmaceuticals Ltd..
Is FETRASIL Right for You?

FETRASIL is recommended for:
Overweight people with an initial Body Mass Index (BMI) of 30 or higher
Or Overweight people with a BMI of 27 or higher if they have medical risk factors such as high blood pressure, diabetes, or high cholesterol.

BMI is an indicator of total body fat, which can be related to the risk of certain diseases and premature death. Your doctor can tell you if your BMI meets these criteria and if FETRASIL might be right for you.


The health information contained herein is provided for informational purposes only and is not intended to replace a discussion with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider and consider the unique characteristics of each patient.

The information contained in FETRASIL.net is intended for use only by INDIA residents. Countries outside of the INDIA may have regulatory requirements, data measurements,or medical practices that may differ from those in the INDIA. Therefore, this information may not be appropriate for use outside the INDIA.

Manufactured in India By: Taj Pharmaceuticals Ltd.(Factory: Plot no. 17-18, industrial area, bilaspur, Himachal pradesh., -174 001, INDIA.,)

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