Each 1ml contains :
Composition:
Meropenem
......................................................................1
g
Meropenem
..................................................................500
mg
Indications :
Intra-abdominal infections, nosocominal
pneumonia, septicaemia, cystic fibrosis,
meningitis, febrile neutropenia.
Description:
The bactericidal activity of meropenem
results from the inhibition of cell wall
synthesis. Meropenem readily penetrates
the cell wall of most Gram-positive and
Gram-negative bacteria to reach
penicillin-binding- protein (PBP)
targets. Its strongest affinities are
toward PBPs 2, 3 and 4 of Escherichia
coli and Pseudomonas aeruginosa;
and PBPs 1, 2 and 4 of Staphylococcus
aureus.
Dosage :
Intra-abdominal infections; nosocominal
pneumonia; septicaemia: Adults:
500mg-1g hrly depending on the severity
and type. IV infusion, over approx. 15
to 30 minutes or as an intravenous bolus
injection (5 to 20 mL) over
approximately 3-5minutes. Child: (3
months to 12 yrs): IV 10 to 40mg/kg
8hrly, or as reqd. Cystic fibrosis;
meningitis: Adults: 2g 8 hrly. Febrile
neutropenia: 1g 8 hrly.
Presentations:
Vial 1 ml
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